Advanced Glycation End Products in Nephrology: Meeting on Advanced Glycosylation End-Products in Nephrology: Much More Than Diabetic Nephropathy, ... Padua, Italy (Contributions to Nephrology)

Rok: 2000
ISBN: 9783805571357
OKCZID: 110195583

Citace (dle ČSN ISO 690):
D'ANGELO, Angela, ed., FAVARO, Silvana, ed. a GAMBARO, Giovanni, ed. Advanced glycation end products in nephrology. [1st ed.]. Basel: Karger, 2001. VIII, 147 s. Contributions to nephrology, Vol. 131.

Anotace

The pathological role of advanced glycation end products (AGEs) and of oxidative-carbonylic stress is well known in the context of diabetes. Moreo ver, there is also strong evidence that they play a pivotal role in the pathogenesis of some chronic disorders related to uremia, and namely to cardiovascular complications and dialysis-related amyloidosis. They may even play a crucial role in the loss of function of the peritoneal membrane in patients on peritoneal dialysis, a problem which limits the duration of such a treatment. Written by authoritative European experts, this publication includes contributions on AGEs as related to diabetic nephropathy, hemodialysis and, particularly, peritoneal dialysis. The topics covered range from basic research (such as novel pathogenic pathways triggered by AGEs) to clinical issues, including substitutive therapy in uremic diabetic patients as well as original and new results from a clinical trial on peritoneal dialysis with a new bag. This publication will be of interest to nephrologists as well as those working in the field of diabetes or otherwise involved in AGE research, giving an idea into what direction research in this complex field is going and which will probably be the major clinical breakthroughs in the near future.

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